To consider the clinical significance of a secondtrimester elevated maternal serum hCG in women carrying singleton, chromosomally normal fetuses. In multiple gestation pregnancies (twins, triplets, and so forth.), calculation of the danger of Down syndrome or Edwards syndrome could be difficult because the quantity of PAPP-A and free beta hCG is increased. The nuchal translucency ultrasound, however, is an assessment that's unique to each fetus and could be carried out independently with…