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The effect of immunotherapy on the subgroup of patients 1 year of age or older who had stage 4 disease, according to the International Neuroblastoma Staging System (INSS), at the time of diagnosis was also analyzed, since this subgroup accounts for the majority of high-risk cases (179 of 226 randomized patients).

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When I apply it it kind of stings and makes my eyes water but within seconds that passes, it also does leave a residue of your face in the morning due to the peeling effect but this can easily be washed off.

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