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Effects of the antianginal drug, ranolazine, on the brain sodium channel Na V1.

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Treatment of isolated working rat hearts with leptin also increases fatty acid β-oxidation of both exogenously and endogenously derived fatty acids, and is associated with a decrease in intramyocardial TAG stores ().

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In separate atrial preparations, 5 μM of ranolazine was effective in terminating persistent AF only in 1 out of 5 atria (Table 2).

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