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I first started having attacks of gout when I was 31. My doctor failed to diagnose me in the right way, so in a couple of month I addressed a rheumatologist, who prescribed me with Allopurinol. The worst thing is that I've heard people who take these pills can no longer deal without them. But having to choose between gout and pills till the end of the life, I chose Allopurinol

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In vitro work has shown that in cultured human aortic endothelial cells, XO is the major source of free radicals and that hypoxanthine and XO increase endothelial dysfunction, which can then be improved by allopurinol.

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We should be aiming for closer working with GPs in primary care; long term condition support, pharmacist prescribers supporting acute and minor ailments, physicians assistant roles, etc.

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