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How long should you take tamoxifen after breast cancer? Tamoxifen has been used in breast cancer therapy for more than 20 years. It's usually given for five years after initial breast cancer treatments (such as surgery, chemotherapy, and radiation).
What time of day should I take my tamoxifen? Tamoxifen comes as a tablet to take by mouth. Tamoxifen is usually taken once or twice a day with or without food. Take tamoxifen at around the same time (s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain anything you do not understand.