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Can gabapentin make RLS worse? However, they may cause a worsening of symptoms for some people after daily use. Anticonvulsants: These agents, such as gabapentin (Neurontin) and gabapentin enacarbil (Horizant), may help relieve the symptoms of RLS as well as any chronic pain or nerve pain.
What diseases cause restless leg syndrome? Other factors associated with the development or worsening of restless legs syndrome include: Chronic diseases. Certain chronic diseases and medical conditions, including iron deficiency, Parkinson's disease, kidney failure, diabetes, and peripheral neuropathy often include symptoms of RLS.


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