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Losartan Potassium: No clinically significant drug interactions have been found in studies of losartan potassium with hydrochlorothiazide, digoxin, warfarin, cimetidine and phenobarbital.

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For Control of Hypertension: The adult initial dose of MICROZIDE (hydrochlorothiazide capsule) is one capsule given once daily whether given alone or in combination with other antihypertensives.

However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require an adjustment in the dose for patients receiving tablets.

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