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Podofilox (podophyllotoxin) is a patient-applied antimitotic drug that causes wart necrosis.

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These proteins also undergo posttranslational modifications, including N-glycosylation and phosphorylation, resulting in further structural diversity, which may explain the greater degree of resistance for the specific agent in which resistance was selected against, as well as the variable degrees of resistance to agents aside from that specific agent.

Among the latter, are the most important compounds in determining the health effects of the fruit and derived products.

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One case described neuropathy onset after several years of treatment with lovastatin; when treatment stopped, the condition improved (Ziajka and Wehmeier 1998).

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During an investigation of the effect of the carcinoclastic compound, podophyllotoxin, on tissue respiration, we observed that injection of this compound into normal rats produced marked reduction of the respiration of spleen, lymph node, and thymus gland slices (1).

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India's Council for Scientific and Industrial Research (CSIR) takes a more pragmatic approach to bridging the divide.

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