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Patients taking each lithium and etodolac might develop toxic blood lithium levels. Additionally, etodolac has been found to interact with sure anti-depressant drugs, corresponding to sertraline or fluoxetine, which might increase risks of stroke, coronary heart attack, and different cardiovascular circumstances. Patients additionally taking ciclosporin can develop kidney toxicity. NSAIDs must be discontinued prior to elective surgical procedure due to a gentle interference with clotting that's characteristic of this group of medicines. etodolac Buy etodolac 30mg fedex vermont. Etodolac is finest discontinued at least four days in advance of surgery. Etodolac metabolites may also trigger a false constructive bilirubin result on a urinalysis test. Using ibuprofen together with etodolac is mostly not recommended. Combining etodolac these medicines may improve the chance of unwanted side effects in the gastrointestinal tract similar to inflammation, bleeding, ulceration, and rarely, perforation. Gastrointestinal perforation is a doubtlessly fatal situation and medical emergency the place a gap types all through the abdomen or intestine. Inside Diseases