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Once-Monthly Aripiprazole Effective in Bipolar Disorder. Currently, the only long-acting injectable antipsychotic that has been approved by the US Food and Drug Administration for the treatment of bipolar I disorder is risperidone (Risperdal, Janssen). Treatment with risperidone requires an injection every 2 weeks.
How does paliperidone work in the brain? Invega tablets contain the active ingredient paliperidone, which is a type of medicine called an atypical antipsychotic. Paliperidone works by blocking the receptors in the brain that dopamine acts on. This prevents the excessive activity of dopamine and helps to control schizophrenia.
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