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As the obstruction becomes more severe, the number of alveoli being inadequately ventilated and perfused increases, and carbon dioxide retention (hypercapnia) and respiratory acidosis develop.

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More children who received FORADIL AEROLIZER 24 mcg twice daily than children who received FORADIL AEROLIZER 12 mcg twice daily or placebo experienced serious asthma exacerbations, as shown in the next table.

At the same time, press down firmly on the center of the dose indicator at the top of the canister with your index finger.

Incident Pneumonia and Mortality in Patients with Chronic Obstructive Pulmonary Disease.

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In a healthy person, the tiny air sacs in the lungs are like balloons.

Corticosteroids are powerful anti-inflammatory drugs.

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This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

Data Synthesis A total of 401 citations were reviewed, of which 16 articles (15 studies) were relevant.

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Glucocorticoid and β-adrenoceptor agonist interactions in asthma.

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If exposed, therapy with varicella zoster immune globulin (VZIG) or pooled intravenous immunoglobulin (IVIG), as appropriate, may be indicated.

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FORADIL AEROLIZER 12 mcg twice daily demonstrated a greater 12-hour FEV 1 AUC compared to placebo on the first day of treatment, after twelve weeks of treatment, and after one year of treatment.

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Results from a meta-analysis by Salpeter and colleagues () showed an increase in respiratory deaths with long-acting β-agonists and a decrease with anticholinergics.

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Report other drugs which affect the heart rhythm (QTc prolongation), such as: dofetilide, pimozide, quinidine, sotalol, procainamide, sparfloxacin.

Aclidinium bromide in patients with chronic obstructive pulmonary disease: efficacy and safety results from ATTAIN (Abstract).

Nevertheless, the number needed to treat to prevent an exacerbation in 1 year was 4, and the number needed to treat to prevent a hospitalization was 32.

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Eventually, the goals of treatment in COPD target beyond the optimisation of lung function.

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By contrast, in Group B, adding formoterol reduced the risk for the first severe exacerbation and for poorly controlled days by 43 and 30%, respectively.

Patients with low lung function benefitted most from the higher maintenance dose.

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The use of repeated injections of small doses of allergen is effective in treating allergic rhinitis, and positive effects may persist even years after treatment has been stopped.

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