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How long does it take for Plavix to get out of your system? After a single, oral dose of 75 mg, Plavix (clopidogrel) has a half-life of approximately 6 hours. It takes 5.5 x half-life of a medicine for it to be out of one's system, therefore Plavix should be eliminated from your system in 5.5 x 6 = 33 hours.
How long should you take clopidogrel for? The new recommendation is that after 12 months if there is no evidence of major bleeding or other problems with clopidogrel aspirin, it is suggested you continue that therapy for an additional 18 months. I know, it seems long. Antiplatelet therapy: at least 12 months, but 18 more?
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