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I was on one Clozapine for more than three years, for my schizophrenia case. This medication managed to produce effects that surpassed my best expectations and hopes. It provided me with complete control over my mood and emotions, my motivation increased many times, I hadn't had a single breakdown since the day I started on Clozapine. For me it is the best solution and I don't even think about changing medicine.

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My son was had a myriad of diagnosis since he was 3 years old - by the time he was 20 he had been hospitalized numerous times, attempted suicide 4 times, and was uncontrollable. He had been on 19 different medicines over the course of this time with no reprieve. His doctor decided to try Clozaril as a last case alternative - I don't even know what to say, within two weeks his anger diminished, with three his personality started to emerge -the medicine completely changed his life. It was like nothing I had ever seen before. He literally transformed with 6 weeks from a boy who couldn't exist in society, could manage his behaviors or aggression and was completely out of touch with reality into a son I had never seen before. He now works full time.

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Naturalistic Comparison of the Long-Term Metabolic Adverse Effects of Clozapine Versus Other Antipsychotics for Patients With Psychotic Illnesses.

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The Cochrane Database of Systematic Reviews (3): CD001949.

Specifically, the success of symptom management and side effects experienced by the patient on the first medication may help predict which medication may be more successful next.

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Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.

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Therapy with neuroleptic agents should be administered cautiously in patients with significant liver disease.

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There was no indication of saturation of tubular transport in the range of clozapine metabolite concentrations occurring in the patient group.

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Drug concentrations in cerebrospinal fluid (CSF) that are assumed to roughly equal unbound concentrations in plasma are available for clozapine from two studies.

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