The DR for TR alone is approximately 59.four % for a FPR of eight.eight % . Addition of TR to mixed screening can enhance the DR from 75 % to 87 % for a FPR of 1.zero % . Table 3 presents the reported DRs and FPRs for additional ultrasound markers alone and in combination with first trimester mixed screening. Most widespread issue for a false negative screening result is NT. Therefore, appropriate training and fixed audit in addition to probably the certification of the competence should be…