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A generic drug is actually its brand-name equivalent, although it doesnt bear the original trademark and looks slightly different.
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Vaccines are the simplest option to forestall infectious illnesses. For instance, for the heart-disease drug Praluent that my company developed, we might present that it effectively lowered dangerous cholesterol” in Section 2 trials of a couple hundred sufferers, but the Section three trial that was required to indicate it prevented heart attacks and improved survival concerned about 20,000 sufferers and about five years. The incompleteness and complexity of the Part D advantages ensured that beneficiaries will likely be confused and that many of them won't see any improvement in their protection ( Bettelheim 2003 ; Pear 2003b ; Stolberg 2003b ). Indeed, many beneficiaries might be worse off if numerous employers drop the prescription drug benefits that they at the moment offer to retirees.
If a platform know-how utilized to manufacture a licensed vaccine or different investigational vaccines is properly characterised, it's potential to make use of toxicology data (e.g., data from repeat dose toxicity research, biodistribution research) and clinical knowledge accrued with different merchandise utilizing the identical platform to assist FIH medical trials for a SARS-CoV-2 vaccine candidate.