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Risperidone also appeared to impair maternal behavior in that pup body weight gain and survival (from Day 1 to 4 of lactation) were reduced in pups born to control but reared by drug-treated dams.

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All efficacy and safety analyses were performed on the intent-to-treat (ITT) analysis set, which included patients who received at least one dose of the study medication during the treatment period.

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Antimanic agents with evidence for efficacy in acute mania include lithium, valproate, olanzapine, aripiprazole, quetiapine, risperidone, ziprasidone, paliperidone, haloperidol and to a lesser extent carbamazepine.

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Individuals who do not find themselves affected by mental illnesses can help those who have been diagnosed with such disorders.

Table 2 Outcome Measures of Effectiveness in the Intention-to-Treat Population.

While reserpine, a medication that also reduces blood pressure, has also been found to decrease psychotic symptoms, the fact that safer, more effective medications now exist has resulted in its being far less frequently used these days.

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