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I was prescribed with Mestinon to treat my ocular myasthenia gravis. I am very surprised to see how effective this medication is after many disappointments with other drugs. Mestinon eliminates almost all the symptoms I have like weakness, inability to control my balance when walking, shortness of breathing and other. Myasthenia gravis is a serious disease. It's not diarrhea and you should be ready for side effects medications may have. With Mestinon I faced indigestion during the first week of treatment, then it disappeared. Now I only have occasional dizziness. But in general the medication is the best thing I have tried for my myasthenia.

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Mestinon has literally given me back my life. Myasthenia gravis was a shocking diagnosis for me. But I decided to struggle for my life and my efforts were praised with this amazing medication. With the help of Mestinon I can walk and cook without assistance. Sometimes I can even write or type like today. Weakness comes back at times, but my condition isn't getting worse for more than two years now! For me it's an excellent result!

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Inadequate reversal of nondepolarizing muscle relaxants: Inadequate reversal induced by nondepolarizing muscle relaxants is possible; manage with manual or mechanical ventilation until recovery is adequate (additional doses not recommended).

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Bias, potential for analytical sloppiness, lack of understanding of basic issues, failure to consider major covariates, and overstating the strengths and precision of the results.

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These side effects may go away during treatment as your body adjusts to the medicine.

The fourth randomised controlled trial involving 35 participants reported a benefit from plasma exchange before thymectomy but this trial was heavily biased.

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Hydrotherapy should not delay the time to diagnosis or treatment with more proven techniques or therapies, and should not be used as the sole approach to illnesses.

Testing a facial muscle (eg, the orbicularis oculi) is useful because most patients suffer from eyelid weakness or ptosis.

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The clinical significance of anti-MuSK antibodies is still under study, but patients with these antibodies are much less likely to have thymic hyperplasia or a thymoma, may be less responsive to anticholinesterase drugs, and may require more aggressive early immunotherapy than patients who have AChR antibodies.

It can produce a temporary improvement in symptoms, but is too expensive for long-term treatment.

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The goal of physical therapy is to improve mobility, restore function, reduce pain, and prevent further injury.

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It sure is taking a long time to re-invent the wheel.

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The quinine in tonic water also produces weakness in some myasthenics, but the effect is usually very mild as the amount of quinine is so small.

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Symptoms are related to cerebral hypoperfusion, with resulting lack of cerebral oxygenation (causing lightheadedness, dizziness, weakness, difficulty thinking, headache, syn cope, or feeling faint) and a compensatory autonomic overreaction (causing palpitations, tremulousness, nausea, coldness of extremities, chest pain, and syncope).

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This leads to fatigable muscles and often involves the eye, causing diplopia and ptosis.

However, this finding is not consistent, and serial Ab titers alone are not reliable.

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Dr Grubb at University of Toldeo has been using Mestinon (and other drugs) for POTS for quite a long time.

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