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Effects of valproate on early and late potassium currents of single neurons: European Neuropsychopharmacology Vol 3(2) Jun 1993, 137-141.
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Valproate causes birth defects; exposure during is associated with about three times as many major abnormalities as usual, mainly with the risks being related to the strength of medication used and use of more than one drug.
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Absence of adverse effects of valpromide in vigilance and psychomotor performances: A double-blind study with 29 volunteers with computerized psychometric and automobile driving tests: Psychologie Medicale Vol 23(9) Sep 1991, 1099-1114.
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Efficacy of Valproate Maintenance in Patients With Bipolar Disorder and Alcoholism: Archives of General Psychiatry Vol 62(1) Jan 2005, 37-45.
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Lithium prevents colchicine-induced apoptosis in rat cerebellar granule neurons: Bipolar Disorders Vol 6(2) Apr 2004, 144-149.
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Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain: Psychopharmacology Vol 158(1) Oct 2001, 100-106.
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The Food and Drug Administration (FDA) approved Depakote for epilepsy treatment in 1983.
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An interaction between aspirin and valproate: The relevance of plasma protein displacement drug-drug interactions": Correction: American Journal of Psychiatry Vol 164(1) Jan 2007, 175.
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It is for this group of patients (acute alcohol hallucinosis) that the advent of a drug with established safety, efficacy and lack of abuse potential is essential.
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