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The following clinically significant, immune-mediated adverse reactions occurred in less than 1% of patients treated with KEYTRUDA: exfoliative dermatitis, uveitis, arthritis, myositis, pancreatitis, hemolytic anemia, partial seizures arising in a patient with inflammatory foci in brain parenchyma, adrenal insufficiency, myasthenic syndrome, optic neuritis, and rhabdomyolysis.

It commemorates the 2 5th anniversary of Merck's Mectizan Donation Program which started in 1987--the longest-running initiative and public-private partnership of its kind--to treat millions in African and South American countries who suffered from the parasitic disease river blindness.

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