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Use of Diuretics in Patients with Hypertension.

Following either oral or intravenous administration of 14C-labeled irbesartan, about 20% of radioactivity is recovered in the urine and the remainder in the feces, as irbesartan or irbesartan glucuronide.

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Elevated systolic or diastolic pressure causes increased cardiovascular risk, and the absolute risk increase per mmHg is greater at higher blood pressures, so that even modest reductions of severe hypertension can provide substantial benefit.

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If high blood pressure is left untreated it can increase the risk of heart disease or stroke.

According to the prescribing information for hydrochlorothiazide, muscle pain has been reported in people taking this medication.

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Use of angiotensin converting enzyme inhibitors (ACEI), angiotensin II receptor blockers (ARBs), beta blockers (BB), calcium channel blockers (CCB), or a combination may also be considered.

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The most common side effects with Hydrochlorothiazide are dizziness, headache, fatigue, and muscle cramps.

Following abrupt cessation of therapy with certain beta-blocking agents, exacerbations of angina pectoris and, in some cases, myocardial infarction have been reported.

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About 14% of an orally-administered dose of losartan is converted to the active metabolite.

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Plasma concentrations of losartan were about twice as high in female hypertensives as male hypertensives, but concentrations of the active metabolite were similar in males and females.

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Neonates with a history of in utero exposure to Losartan Potassium and Hydrochlorothiazide: If oliguria or hypotension occurs, direct attention toward support of blood pressure and renal perfusion.

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Hydrochlorothiazide is a drug used to prevent water retention in patients.

According to the manufacturer, hydrochlorothiazide (HCTZ) should be used cautiously by patients who have diabetes or prediabetes.

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DYAZIDE (hydrochlorothiazide and triamterene) when using high doses for prolonged periods or in patients on a salt-restricted diet.

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No significant drug-drug pharmacokinetic interactions have been found in interaction studies with hydrochlorothiazide, digoxin, warfarin, cimetidine and phenobarbital.

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Talk with your doctor about making changes to your lifestyle that may help this medication work better (such as stress reduction programs, exercise, and dietary changes).

Combined with various other medicines, Hydrochlorothiazide is likewise used to deal with high blood stress.

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Losartan Potassium and Hydrochlorothiazide Tablets and certain other medicines may interact with each other.

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Effectiveness and Tolerability of Fixed-Dose Combination Enalapril plus Nitrendipine in Hypertensive Patients.

In a few patients with cor pulmonale, as suspected in this patient, right ventricular hypertrophy regresses when the pulmonary disease is improved with long term corticosteroids.

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Race: In the LIFE study, Black patients treated with atenolol were at lower risk of experiencing the primary composite endpoint compared with Black patients treated with losartan.

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